Resource Type

Journal Article 67

Year

2023 7

2022 5

2021 6

2020 2

2019 3

2018 4

2017 9

2016 7

2015 1

2014 2

2011 2

2010 1

2009 6

2008 4

2006 1

2003 1

2001 1

open ︾

Keywords

RNA interference 4

DNA 3

Full-duplex 2

Interference 2

RNA 2

cancer 2

2019-nCoV 1

2D-DIGE 1

Manihot esculenta 1

pqqB 1

ACE2 1

Achievable rate region 1

Adaptive robust beamformer 1

Anti-RNA viruses 1

BSR-seq 1

BSR-seq / PmUGT72B3 / Prunus mume / UDP-glycosyltransferase / weeping shoots / WGCNA 1

Beamforming 1

Blocking matrix 1

Business process execution language 1

open ︾

Search scope:

排序： Display mode:

Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 57-60 doi: 10.1007/s11684-009-0003-z

Abstract: The aim of the present study was to construct the lentiviral RNA interference (RNAi) vector of rat OBRb

Keywords： receptors     leptin     RNA interference     lentivirus vector    

HTML PDF Collect

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: The aim of this study is to investigate the effects of RNA interference (RNAi) targeting angiotensin

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

HTML PDF Collect

RNA-Based Biocontrols—A New Paradigm in Crop Protection Review

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Engineering 2020, Volume 6, Issue 5,   Pages 522-527 doi: 10.1016/j.eng.2019.09.008

Abstract: Over the last years, the RNA interference (RNAi) process has been identified as a very promising newRNA-based active ingredients (AIs) possess a unique mode of action and can be implemented via both geneticRNA-based AIs promise to deliver the selectivity and sustainability desired in future crop protectionresearch progress toward RNA-based biocontrols against the Colorado potato beetle (CPB), corn rootwormMany challenges still exist on the road to the implementation of a broad range of RNA-based products

Keywords： RNA-based biocontrols     RNA interference (RNAi)     Colorado potato beetle (CPB)     Corn rootworm (CRW)     Soy    

HTML PDF Collect

Gene silencing efficiency of shRNA expression vectors targeting Cx43

Cuihong ZHENG, Yunxia WU, Guangying HUANG, Wei WANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 130-135 doi: 10.1007/s11684-009-0030-9

Abstract: In order to further investigate the effect of Cx43 in acupuncture treatment, RNA interference techniquewas used to construct small hairpin RNA (shRNA) expression vectors targeting Cx43 and identify the efficiencyof RNA interference in NIH/3T3 cell lines for further use .

Keywords： RNA interference     connexin 43     small hairpin RNA (shRNA)     acupuncture    

HTML PDF Collect

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy for food security in Africa

Maliwan NACONSIE,Peng ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 285-294 doi: 10.15302/J-FASE-2016119

Abstract: overexpression of nutritious storage proteins and improving cassava resistance to viral diseases by RNAinterference.

Keywords： Manihot esculenta     protein enhancement     RNA interference     transgenesis     virus resistance    

HTML PDF Collect

Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2,   Pages 178-185 doi: 10.1007/s11705-016-1558-2

Abstract: Ribozymes are widespread, and catalyze some extremely important reactions in the cell. Mechanistically most fall into one of two classes, using either metal ions or general acid-base catalysis. The nucleolytic ribozymes fall into the latter class, mostly using nucleobases. A sub-set of these use a combination of guanine base plus adenine acid to catalyze the cleavage reaction. New ribozymes are still being discovered at regular intervals and we can speculate on the potential existence of ribozymes that catalyze chemistry beyond phosphoryl transfer reactions, perhaps using small-molecule coenzymes.

Keywords： RNA catalysis     RNA structure     catalytic mechanism    

HTML PDF Collect

Lentivector-mediated RNAi efficiently downregulates expression of murine cdk4 gene

Feng JIANG PhD , Xuezhen WANG PhD , Zheng XUE MD , Suming ZHANG PhD , Siyu FANG BM , Min ZHANG MD, PhD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 287-291 doi: 10.1007/s11684-009-0050-5

Abstract: explore the role of cyclin-dependent kinase 4 (cdk4) in neurodegenerative diseases, lentiviral-delivered RNAinterference (RNAi) was used to silence the expression of the murine cdk4 gene .Interference efficiency of the lentivirus expressing cdk4-siRNA was determined by reverse transcriptase-PCR

Keywords： cyclin-dependent kinase 4     RNA interference     plasmid     lentiviral vector    

HTML PDF Collect

Elastoplastic frictional contact problem study on interference fits of compressor

ZHANG Hongwu, WU Changhua, LIAO Aihua

Frontiers in Energy 2008, Volume 2, Issue 3,   Pages 313-319 doi: 10.1007/s11708-008-0026-1

Abstract: A locomotive-type turbocharger compressor with 24 blades under combined centrifugal and interference-fitdecrease the difficulty of the assembly process and ensure the safety of the working state, the amount of interference

Keywords： computation     thickness     interference-fit     interference     unspecified    

HTML PDF Collect

Laser interference fabrication of large-area functional periodic structure surface

Lei WANG, Zi-Han WANG, Yan-Hao YU, Hong-Bo SUN

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 4,   Pages 493-503 doi: 10.1007/s11465-018-0507-9

Abstract: The laser interference technique in particular has received attention because of its simplicity, lowHere, we reviewed the work on laser interference fabrication of large-area functional periodic structuresFor the common cases, four-beam interference and multi-exposure of two-beam interference were emphasizedThe relations between multi-beam interference and multi-exposure of two-beam interference were comparedPerspectives on future directions and applications for laser interference were presented.

Keywords： laser interference     four-beam interference     multi-exposure of two-beam interference     additive fabrication    

HTML PDF Collect

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Strategic Study of CAE 2003, Volume 5, Issue 7,   Pages 17-23

Abstract:

The structure, reproduction, replication and transcription of RNA viruses were introduced.Antivirus strategies including design of anti - SARS drugs, RNA interference, DNA vaccine delivery systemThese examples imply the interactions of RNA viruses with proteins, DNA, and polysaccharides.

Keywords： Anti-RNA viruses     protein     DNA     polysaccharide     biomaterials    

HTML PDF Collect

Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression Article

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Engineering 2023, Volume 21, Issue 2,   Pages 187-193 doi: 10.1016/j.eng.2021.12.007

Abstract:

Osteosarcoma (OS) is a malignant mesenchymal tissue tumor known to occur in children and adolescents, and pulmonary metastasis often leads to death in these patients. The mechanism underlying OS progression remains unclear. Therefore, identifying new therapeutic targets and treatment modalities for OS is urgently needed. Abnormally expressed non-coding circular RNAs (circRNAs) are crucial for the occurrence and development of OS. The purpose of this study was to explore the expression and role of a novel circRNA circ_000203 in OS and elucidate the underlying mechanism. circ_000203 was demonstrated highly expressed in OS cell lines and tissues, and circ_000203 knockdown significantly inhibited OS progression in vitro and in vivo. Furthermore, we found that circ_000203 is a sponge of miR-26b-5p, an upstream regulator of bone morphogenetic protein receptor 2 (BMPR2). Thus, the overexpression of BMPR2 could reduce the inhibitory effect on OS progression. This indicates that knockdown of circ_000203 suppresses OS progression through microRNA (miRNA)-mediated BMPR2 downregulation. Our findings provide important insights for understanding the occurrence and development of OS. 

Keywords： Non-coding RNA     Osteosarcoma     CircRNA     Molecular mechanism     Knockdown    

HTML PDF Collect

with multi-walled carbon nanotubes: preparation, characterization, and application for electromagnetic interference

Jian LI,Caichao WAN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 4,   Pages 341-346 doi: 10.15302/J-FASE-2015082

Abstract: In addition, the aerogels show a high electromagnetic interference (EMI) value of 19.4 dB.

Keywords： cellulose aerogels     carbon nanotubes     electromagnetic interference shielding     composites    

HTML PDF Collect

Electromagnetic interference modeling and suppression techniques in variable-frequency drive systems

Le YANG, Shuo WANG, Jianghua FENG

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 3,   Pages 329-353 doi: 10.1007/s11465-018-0466-1

Abstract:

Electromagnetic interference (EMI) causes electromechanical damage to the motors and degrades the

Keywords： variable-frequency drive (VFD)     electromagnetic interference (EMI)     motor drive modeling     EMI noise suppression    

HTML PDF Collect

Experimental study of aerodynamic interference effects on aerostatic coefficients of twin deck bridges

Zhiwen LIU , Zhengqing CHEN , Gao LIU , Xinpeng SHAO ,

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 3,   Pages 292-298 doi: 10.1007/s11709-009-0048-8

Abstract: The aerodynamic interference effects on aerostatic coefficients of twin deck bridges with large spanand torque coefficients of windward and leeward decks are also affected slightly by the aerodynamic interferenceAnd the aerodynamic interference effects on lift and torque coefficients of twin decks can be neglected

Keywords： twin decks     aerodynamic interference effects     aerostatic coefficients     wind tunnel test    

HTML PDF Collect

Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 166-170 doi: 10.1007/s11684-008-0030-1

Abstract: Murine Rip2 small interfering RNA (siRNA) plasmids were constructed and transfected into macrophage and
HTML PDF Collect

Title Author Date Type Operation

Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Journal Article

Effects of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

RNA-Based Biocontrols—A New Paradigm in Crop Protection

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Journal Article

Gene silencing efficiency of shRNA expression vectors targeting Cx43

Cuihong ZHENG, Yunxia WU, Guangying HUANG, Wei WANG

Journal Article

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy for food security in Africa

Maliwan NACONSIE,Peng ZHANG

Journal Article

Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Journal Article

Lentivector-mediated RNAi efficiently downregulates expression of murine cdk4 gene

Feng JIANG PhD , Xuezhen WANG PhD , Zheng XUE MD , Suming ZHANG PhD , Siyu FANG BM , Min ZHANG MD, PhD ,

Journal Article

Elastoplastic frictional contact problem study on interference fits of compressor

ZHANG Hongwu, WU Changhua, LIAO Aihua

Journal Article

Laser interference fabrication of large-area functional periodic structure surface

Lei WANG, Zi-Han WANG, Yan-Hao YU, Hong-Bo SUN

Journal Article

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Journal Article

Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Journal Article

with multi-walled carbon nanotubes: preparation, characterization, and application for electromagnetic interference

Jian LI,Caichao WAN

Journal Article

Electromagnetic interference modeling and suppression techniques in variable-frequency drive systems

Le YANG, Shuo WANG, Jianghua FENG

Journal Article

Experimental study of aerodynamic interference effects on aerostatic coefficients of twin deck bridges

Zhiwen LIU , Zhengqing CHEN , Gao LIU , Xinpeng SHAO ,

Journal Article

Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Journal Article